Updates on the management of Multiple Myeloma

Guidelines by the Hematology and Bone Marrow Transplant Unit at Hospital Universitário Walter Cantídio

Authors

  • Sérgio Parente Filho Hospital Universitário Walter Cantídio
  • Jacqueline Holanda de Souza Souza University Hospital Walter Cantídio https://orcid.org/0000-0002-6593-2357
  • Germana Franck de Souza Bastos Rocha University Hospital Walter Cantídio
  • João Paulo Vasconcelos University Hospital Walter Cantídio
  • Karine Sampaio Nunes Barroso University Hospital Walter Cantídio https://orcid.org/0000-0002-5346-9414
  • Beatriz Stella Gomes de Souza Pitombeira Araújo University Hospital Walter Cantídio
  • Livia Andrade Gurgel University Hospital Walter Cantídio
  • Rafael da Nóbrega de Alencar University Hospital Walter Cantídio
  • Lucas Freire Castelo University Hospital Walter Cantídio
  • Fernando Barroso Duarte University Hospital Walter Cantídio https://orcid.org/0000-0001-5170-695X

DOI:

https://doi.org/10.46765/2675-374X.2025v6n1p249

Abstract

Multiple Myeloma (MM) is a mature hematological neoplasm characterized by histological infiltration (bone marrow and/or extramedullary plasmacytomas) by clonal plasma cells and the presence of one or more defining events, including anemia, renal impairment, osteolytic lesions, and hypercalcemia. The management of MM has drammaticaly evolved over the past few years. However, new drugs are not available in the Brazilian public health service and treatment is still a challenge, especially in the relapsed/refractory setting. We herein summarize the updates in MM management and make recommendations for care in an optimal scenario and in the Brazilian public health service.

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Published

01/22/2025

How to Cite

Parente Filho, S., Souza, J. H. de S., Rocha, G. F. de S. B. ., Vasconcelos, J. P. ., Barroso, K. S. N., Araújo, B. S. G. de S. P. ., … Duarte, F. B. . (2025). Updates on the management of Multiple Myeloma: Guidelines by the Hematology and Bone Marrow Transplant Unit at Hospital Universitário Walter Cantídio. JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY, 6(1), 249. https://doi.org/10.46765/2675-374X.2025v6n1p249

Issue

Vol. 6 No. 1 (2025): Journal of Bone Marrow Transplantation and Cellular Therapy

Section

Protocols of conduct

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