Haploidentical Hematopoietic Stem-cell Transplant for High-Risk Acute Myeloid Leukemia in a Kidney Transplant Recipient: Case Report

Authors

  • Hercules Amorim Mota Segundo Walter Cantídio University Hospital https://orcid.org/0009-0000-1494-078X
  • Ana Vitoria Magalhães Chaves Federal University of Ceará (UFC), Fortaleza, Ceará, Brazil
  • Thays Araújo Freire de Sá Walter Cantídio University Hospital (HUWC-UFC)
  • Karine Sampaio Nunes Barroso Walter Cantídio University Hospital (HUWC-UFC)
  • Raimundo Messias de Araújo Filho Walter Cantídio University Hospital (HUWC-UFC)
  • Paula Frassinetti Castelo Branco Camurça Fernandes Walter Cantídio University Hospital (HUWC-UFC)
  • Fernando Barroso Duarte Walter Cantídio University Hospital (HUWC-UFC)

DOI:

https://doi.org/10.46765/2675-374X.2025v6n1p264

Abstract

Solid organ transplantation is associated with a higher incidence of malignancies. Among them, acute myeloid leukemia has high morbidity and mortality, and its cure is only possible through allogeneic hematopoietic stem cell transplantation for high-risk disease. Case report: A 32-year-old female who underwent a kidney transplant eight years before was diagnosed with high-risk acute myeloid leukemia. She underwent induction therapy with “7+3”, achieving complete remission with measurable residual disease detectable by flow cytometry. She then underwent a myeloablative haploidentical allogeneic transplant, achieving complete remission, free of graft-versus-host disease, with a functioning renal graft.

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Published

06/13/2025

How to Cite

Amorim Mota Segundo, H., Magalhães Chaves, A. V., Araújo Freire de Sá, T., Sampaio Nunes Barroso, K., Messias de Araújo Filho, R., Frassinetti Castelo Branco Camurça Fernandes, P., & Barroso Duarte, F. (2025). Haploidentical Hematopoietic Stem-cell Transplant for High-Risk Acute Myeloid Leukemia in a Kidney Transplant Recipient: Case Report. JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY, 6(1), 264. https://doi.org/10.46765/2675-374X.2025v6n1p264

Issue

Vol. 6 No. 1 (2025): Journal of Bone Marrow Transplantation and Cellular Therapy

Section

Case reports

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